The remarkable discoveries of the past 100 years or so have not diminished the marvel—quite the contrary. But they have removed the central _____ regarding the nature of life. We can now see that all living things are made of cells: small, membrane-enclosed units filled with a concentrated aqueous solution of chemicals and endowed with the extraordinary ability to create copies of themselves by growing and then dividing in two.

Which of the following is the BEST fit in the blank?

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